Consult your doctor before starting metformin, especially if you have kidney or liver problems. Metformin can cause gastrointestinal issues like nausea, diarrhea, and vomiting. These usually lessen over time, but inform your doctor if they persist or worsen.
Common Side Effects
Less common, but still possible, side effects include a metallic taste in the mouth, decreased vitamin B12 levels (requiring monitoring and potential supplementation), and lactic acidosis (a rare but serious complication – seek immediate medical attention if you experience unusual muscle pain, weakness, or difficulty breathing).
Less Frequent, but Serious Side Effects
Metformin can interact with other medications. Always inform your doctor and pharmacist of all medications, supplements, and herbal remedies you are taking. Proper monitoring of your kidney function is necessary, especially if you’re older or have pre-existing kidney conditions.
Medication Interactions & Monitoring
| ACE inhibitors | Increased risk of lactic acidosis |
| Diuretics | May increase risk of dehydration, worsening kidney function |
| Iodine-based contrast dyes | Temporary discontinuation of metformin may be necessary before procedures |
Regular blood tests can help your doctor monitor your kidney function and vitamin B12 levels. This proactive approach helps ensure safe and effective metformin use.
When to Contact Your Doctor
Contact your doctor immediately if you experience severe stomach upset, unusual fatigue, rapid breathing, or muscle pain. They can assess your situation and provide appropriate guidance.


