Always inform your doctor about all medications you take, including over-the-counter drugs, herbal supplements, and vitamins, before starting Lodine. This allows your doctor to assess potential interactions and adjust your treatment plan accordingly.
Common Drug Interactions
Lodine, containing etodolac, can interact with certain medications. For instance, concurrent use with anticoagulants like warfarin may increase bleeding risk. Simultaneous use with nonsteroidal anti-inflammatory drugs (NSAIDs) may heighten the chance of gastrointestinal complications. Also, be aware that Lodine can affect the effectiveness of diuretics and certain medications for hypertension.
Specific Recommendations
Aspirin: Combining Lodine with aspirin can raise the risk of stomach ulcers. Discuss with your doctor safe alternatives for pain relief if you require both medications. Lithium: Lodine may increase lithium levels in your blood, potentially leading to toxicity. Regular monitoring of lithium levels is necessary while taking Lodine. Methotrexate: Combining Lodine and methotrexate can increase methotrexate’s toxicity. Close monitoring is required to manage this interaction. Your doctor might adjust the methotrexate dosage. Diuretics: Lodine’s anti-inflammatory effect might lessen the diuretic’s effectiveness. This may affect blood pressure control; your doctor will likely adjust your medications.
Seeking Professional Advice
This information is for educational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. They can help you manage potential drug interactions and ensure your safety. They can also discuss alternative treatment options should interactions be unavoidable or pose significant risk.
Reporting Side Effects
Report any unusual symptoms or side effects to your doctor or pharmacist immediately. This includes stomach pain, bleeding, easy bruising, changes in bowel movements, or unusual fatigue.
