Always inform your doctor and pharmacist about all medications, vitamins, and herbal supplements you take, including over-the-counter drugs. Warfarin interacts with many substances, potentially affecting its effectiveness and increasing bleeding risk. Some key examples include:
Common Interactions
Nonsteroidal anti-inflammatory drugs (NSAIDs): Ibuprofen, naproxen, and aspirin can significantly increase bleeding risk when combined with warfarin. Avoid these unless explicitly directed by your doctor.
Antibiotics: Certain antibiotics, like ciprofloxacin and metronidazole, can alter warfarin’s effectiveness. Your doctor may adjust your warfarin dose while taking these antibiotics.
Antifungal medications: Fluconazole and ketoconazole can heighten warfarin’s effects, raising your chance of bleeding. Close monitoring is necessary.
Herbal supplements: Ginkgo biloba, ginseng, and St. John’s wort can interact with warfarin and increase bleeding. Avoid these unless your doctor approves.
Vitamin K-rich foods: Green leafy vegetables like spinach and kale contain vitamin K, which counteracts warfarin’s effects. Maintain a consistent intake of vitamin K-rich foods to prevent unpredictable changes in blood clotting.
Additional Considerations
Regular blood tests are vital to monitor your INR (International Normalized Ratio) and adjust your warfarin dosage as needed. This ensures your blood thins appropriately. Any changes in your medication regimen should be communicated immediately to your physician or pharmacist to avoid potential complications.
