Avoid taking amoxicillin with certain medications. Specifically, taking it alongside methotrexate increases the risk of methotrexate’s side effects. Also, probenecid reduces amoxicillin’s excretion, potentially leading to higher levels in your blood. Always inform your doctor about all medications you’re taking, including over-the-counter drugs and supplements.
Antacids and Other Medications
- Antacids containing aluminum or magnesium can decrease amoxicillin absorption. Separate these by at least 2 hours. Oral contraceptives may have reduced effectiveness while taking amoxicillin; consider alternative birth control methods. Warfarin’s anticoagulant effect may be enhanced; regular blood monitoring is recommended during concurrent use.
Food and Drink
Generally, food doesn’t significantly impact amoxicillin absorption. However, taking it with food might reduce stomach upset for some individuals.
Alcohol
Avoid alcohol consumption while on amoxicillin, as it may increase the risk of liver damage. Consult your doctor if you have any concerns.
Specific Interactions
Allopurinol: May increase the chance of skin reactions. Chloramphenicol: May reduce amoxicillin’s effectiveness. Cyclosporine: Amoxicillin may decrease the effectiveness of cyclosporine.
This information is not exhaustive. Consult your physician or pharmacist for personalized advice regarding potential drug interactions with Amoxicillin, especially if you have pre-existing health conditions or are taking multiple medications. They can provide the most accurate and up-to-date guidance.
