Combining naproxen and prednisone increases your risk of kidney problems. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), reduces blood flow to the kidneys. Prednisone, a corticosteroid, can raise blood pressure and affect kidney function independently. This combination may cause fluid retention, and reduce kidney filtration, potentially leading to kidney damage.
Monitoring Your Kidney Function
Regular checkups with your doctor are vital. Blood tests monitoring creatinine and blood urea nitrogen (BUN) levels assess kidney function. Your doctor will use these results to guide your treatment and adjust medication as needed. Report any signs of kidney problems immediately, including swelling in your legs or ankles, changes in urination, or unexplained fatigue.
Minimizing Risk
Adequate hydration is crucial. Drink plenty of water to support kidney function and help flush out any potential toxins. Your doctor may recommend a lower dose of either medication or suggest alternative pain relievers. Open communication with your doctor ensures safe and effective management of your medications.
Specific Risk Factors
Existing kidney disease significantly increases the risk of complications. Pre-existing hypertension or heart failure also heighten this risk. Individuals with these conditions should discuss potential risks and alternatives with their physician before combining these medications. Regular monitoring is especially important for these patients.
