Begin with the lowest effective dose, typically 500mg once daily. Your doctor will adjust this based on your blood sugar levels and response to treatment.
Adjusting Your Dosage
Increased Dosage: If your blood sugar remains high after several weeks on the initial dose, your doctor might increase it to 500mg twice daily, then 850mg twice daily, or 1000mg twice daily. This gradual increase allows your body to adapt and minimizes side effects.
Extended-Release Formulations: These are often preferred due to their slower release, reducing the chance of gastrointestinal upset. They usually come in higher doses (e. g., 500mg, 750mg, 1000mg once daily), and your doctor will determine the appropriate starting dose.
Considering Other Factors
Kidney Function: Metformin dosage is heavily influenced by kidney health. Reduced kidney function often necessitates a lower dose or a different medication altogether. Your doctor will check your kidney function regularly.
Individual Response: Everyone responds to metformin differently. Some individuals require higher doses to achieve adequate blood sugar control, while others may experience side effects at lower doses. Open communication with your doctor is key.
Potential Side Effects & Management
Common side effects include nausea, diarrhea, and stomach upset. These are usually mild and temporary. Drinking plenty of water with meals, starting with a lower dose, and taking metformin with food can help mitigate these effects. Severe side effects are rare but require immediate medical attention.
Important Note
This information is for educational purposes only and does not constitute medical advice. Always consult your doctor or other qualified healthcare professional before starting, stopping, or changing any medication, including metformin.


